Sugar Substitutes – Are They Safe? (Part 2)

In this article we’ll cover the most commonly used sugar alcohols, Stevia, and how sugar substitutes may affect our appetites.

Be sure to check out Part 1 of this article here if you haven’t already! Get the lowdown on what a Sugar Substitute is, as well as info on the most widely used artificial sweeteners!

Sugar alcohols are a hydrogenated form of a carbohydrate, similar but slightly different to the molecular structure of other sugars. Unlike artificial sweeteners, sugar alcohols are actually less sweet than sugar, with their sweetness compared to sugar varies depending on the sugar alcohol. However, because they taste much more similar to table sugar, they are frequently mixed with artificial sweeteners to create a taste comparable to table sugar. Additionally, sugar alcohols do have calories. On average, they contain approximately 2 kcal per gram. Because of this slight amount of calories contained, sugar alcohols can have an affect on an individual’s blood sugar levels. However, sugar alcohols are partially absorbed by our bodies in the small intestine (rather than almost immediately with common sugar), and so have a much more negligible effect on our blood sugar – again, a very important concern for diabetics. Depending on the country you live or purchase sugar alcohols, they can either be labeled as calorie free (as in the United States), or labeled as having few calories (as in Britain). A word of caution: our bodies are not able to fully breakdown and assimilate sugar alcohols, and thus over-consumption can lead to bloating, flatulence, and even diarrhea. Moderation is key.

Erythritol and Xylitol are two of the most commonly used sugar alcohols for food consumption, as they taste most similar to table sugar and have little if any after taste. Erythritol is approximately 60-70% as sweet as sugar, while Xylitol is approximately 90% as sweet as sugar. However, both are frequently labeled and sold as being the same sweetness as table sugar. Erythritol is more fully absorbed by our bodies than any other sugar alcohol, and thus has the least amount of flatulent or laxative affects. Research on Xylitol has been shown it to reduce harmful strains harmful micro-organisms. Specifically, it has been shown to reduce strains of Mutans streptococci, a group of bacteria shown to be a significant contributor to tooth decay.

Stevia is one of the newest sugar substitutes widely available for sale and used for food consumption in the United States, although has been used for decades to centuries in other countries (such as Japan). It is an herb of the species Stevia rebaudiana, and frequently referred to as sweet leaf. Stevia is approximately 300 times sweeter than sugar! Stevia does has marked aftertaste that some find undesirable, and is thus frequently mixed with sugar alcohols when used in food products. If small amounts of Stevia are used, the aftertaste is less marked. Stevia extract is used for processed food consumption, and is labeled as rebaudioside A. Stevia has been used for centuries by the indigenous people of Paraguay, where it was used a folk remedy to help control blood sugar. Recent research has validated this remedy, showing Stevia as being beneficial to help regular blood glucose levels.

Do Sugar Substitutes Affect Our Appetites? Various studies have been conducted through the years regarding whether sugar substitutes affect our metabolism in direct ways that could trigger our body’s desire to consume more calories or even directly affect our body’s metabolism and systems for storing fat. Sugar substitutes generally do not exist in nature (perhaps other than Stevia), and thus our bodies have evolved to associate a significant number of calories with a sweet flavor. Studies within the past few years on rats have shown that rats fed a surplus diet sweetened with saccharin (an artificial sweetener) gained more weight than rats fed a surplus diet sweetened with glucose or sucrose. When the rats’ core temperature was analyzed, the rats fed artificial sweeteners had a lower core temperature than those fed with glucose or sucrose immediately after eating. Core temperature is an indication of metabolism – a lower core temperature in rats fed artificial sweeteners indicated that the mechanism in the rats’ required to burn excess calories was not triggered, leading to lower overall metabolic rate. Additionally, the rats fed artificial sweeteners ate more total calories than rats fed glucose/sucrose.

While no studies have been conducted on humans regarding artificial sweeteners and metabolism, it is important to understand that artificial sweeteners recreate a taste our bodies are equipped to handle in a very specific manner. While we can’t say if they will in fact slow our metabolism, we do know that many people will crave more sweets the more they eat. Simply because a food contains artificial sweeteners, it does not mean it can be eating to excess – it still contains whatever calories it would have without sugar.

If you’re going to eat a cookie, eat a cookie. Don’t eat the whole box!

If you’re having trouble with sugar cravings, be sure to check out: Understanding Sugar Cravings!

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Sugar Substitutes – Are They Safe? (Part 1)

Many people are attempting to limit calories in their diet, and one of the many ways this can be accomplished is by limiting your sugar intake. Many herbs have traditionally been used as sugar alternatives, and since the late 1800s artificial sweeteners (man-made substances that mimic the sweetness of sugar) have also been utilized in our food. While we know that white sugar (sucrose) itself is devoid of nutrients, and even requires additional nutrients for your body to process, spikes our blood sugar, and can be a leading cause of being overweight and obesity, what is the safety of sugar substitutes? Proponents of sugar substitutes argue their benefit in helping to reduce calories and limit sugar intake (especially important and necessary for those with diabetes!). Opponents of sugar substitutes argue that many have toxic components, but can also overstimulate our taste buds and cause us to crave more sugar and food!

A crucial defining point to sugar substitutes is that they are actually sweeter than sugar itself. This means the amount of a sugar substitute required to get its ‘sweet effect’ is negligible compared to sugar. Because of this, and their very nature, sugar substitutes have either no caloric value to our bodies, or a very minimal caloric value. For those looking to trim up a bit, this can be quite important as a means of decreasing calorie intake. Sugar substitutes primarily consist of artificial sweeteners. The four major artificial sweeteners consumed in the United States include:

  • Acesulfame Potassium (Acesulfame K, Ace K, and Sunnett)
  • Saccharin (Sweet N Low)
  • Aspartame (Equal, Nutra-Sweet)
  • Sucralose (Splenda)

New sugar substitutes available include sugar alcohols and herbs:

  • Erithrytol
  • Xylitol
  • Stevia, an herb (rebiana, Truvia).

Let’s look at each sugar substitute individually:

Acesulfame Potassium was developed in the late 1980s, and is widely consumed in manufactured and packaged foods. It is 200 times sweeter than sugar. In high concentrations, Acesulfame K is bitter, and so is usually mixed with other sugar substitutes. The FDA has cleared Acesulfame K for human consumption, and backs their decision by citing over 90 studies as to its safety. Opponents of Acesulfame K cite conflicting studies, especially regarding a specific component it contains known as methylene chloride. Methylene chloride is as known potent carcinogen – a cancer causing substance – and has also been linked to kidney and liver damage, nausea, and headaches.

Saccharin was accidentally discovered in the late 1870s by a chemist working to develop coal tar derivatives, who happened to discover a sweet taste on his hand. Since the 1950s, saccharin has been used as a sugar substitute in our foods, and is commonly found on tables everywhere. Saccharin can range anywhere from 200-700 times sweeter than sugar. Studies in the 1970s indicated that saccharin could cause bladder cancer in mice, but the FDA confirms that this risk is not major in humans. Ever since the early 1900s, saccharin has had a bumpy road to being legal to sell for food consumption. The director of the bureau of chemistry for the USDA in 1907, Harvey Wiley, stated that saccharin is “extremely injurious to health.” It took another 50 years to legalize saccharin, and the FDA itself has put saccharin up for review and attempted to ban its sale. Other than being potentially carcinogenic, saccharin has also been linked to allergic reactions, headaches, and breathing issues.

Aspartame was discovered in 1965 by a chemist attempting to develop an anti-ulcer drug. Aspartame is about 200 times sweeter than sugar. Originally cleared for food consumption in 1974, objections by a neuroscientist put the approval on hold. It wasn’t until 1981 and 1983 that aspartame was approved for both dry and liquid goods, respectively. Perhaps more than any other sugar substitute, controversy abounds around aspartame’s safety. Because of the large amount of controversy, more tests have been performed regarding aspartame than any other substitute, as well. The FDA states that aspartame has been thoroughly tested, perhaps more than any other food additive, and that it is safe for consumption. The main opposition toward aspartame comes in two parts. Firstly, aspartame is composed of 50% phenylalanine. People with a genetic disorder known as phenylketonuria (PKU) cannot metabolize phenylalanine, which can lead to lethal concentrations in the brain, and so must avoid aspartame. Secondly, aspartame also contains approximately 10% methanol, or wood alcohol, which breaks down into formaldehyde in the human body. Formaldehyde is a known neurotoxin, symptoms which include gastrointestinal disturbances, memory lapses, numbness and pain in bodily extremities, retinal damage and blindness, and is also a known carcinogen.

Sucralose is the newest of the common artificial sweeteners, have been confirmed for consumption in 1998 under the brand name Splenda. Sucralose is 600 times sweeter than sugar. Because of the mild flavor of sucralose, it is much more favorable to most people compared to other artificial sweeteners. Before clearing sucralose for consumption, over 110 studies were reviewed by the FDA, and it was deemed that sucralose posed no toxic carcinogenic, neurological, or reproductive dangers. However, no long term toxicity studies have been conducted on humans. Sucralose is made from actual sugar, but the chemical process it undergoes involves chlorination, and thus transforms the sugar into a new substance. It is this primarily this chlorination process that brings the safety of sucralose into question. A number of studies, including those reviewed by the FDA, indicate that approximately 15% of sucralose ingested by the body is not eliminated in a timely fashion. Opponents argue by not eliminating even this small amount of sucralose over a long period of time could result in chlorine toxicity.

Stay tuned later this week for Part 2, as I cover the sugar alcohols, Stevia, and how sugar substitutes affect our appetites!